High Doses of Clopidogrel to Overcome Genetic Resistance
نویسندگان
چکیده
منابع مشابه
Role of genetic factors on the effect of additional loading doses and two maintenance doses used to overcome clopidogrel hyporesponsiveness.
BACKGROUND AND OBJECTIVE Additional loading doses and higher maintenance doses (MDs) have been used to overcome hyporesponsiveness of clopidogrel. We aimed to investigate whether genetic polymorphisms of two cytochromes (CYP2C19 and CYP2C9) and ABCB1 modify effect of such dose-adjustment strategy. MATERIALS AND METHODS We enrolled 118 patients undergoing elective or acute percutaneous coronar...
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ژورنال
عنوان ژورنال: JACC: Cardiovascular Interventions
سال: 2011
ISSN: 1936-8798
DOI: 10.1016/j.jcin.2011.03.002